Brain Reorganization in Healthy Aging
Extensive literature has demonstrated that the spatial and functional organization of brain regions shows age-related alterations in later life. The aim of this project is to combine brain functional imaging data with cognitive and behavioral information to identify the role of spatial and functional reconfigurations of the brain networks to predict cognitive decline and variability associated with aging.
The successful completion of this project will provide an integrative view of the reconfiguration of the major brain networks across cognitive states in healthy aging and will quantify its association with cognitive decline in older healthy individuals. By mapping the brain functional connectome underlying late adulthood, this work has the potential to elucidate how dysfunction of the brain networks contributes to cognitive aging in healthy and neurodegenerative conditions.
Participate
Our studies are actively seeking participants for research studies. Please fill out the form below if you would like to sign up. If you have any questions about participation, please email BRAIC.Lab@boystown.org or call (531) 355-6703 and we will get back to you.
Relevant Publications:
G. E. Doucet, N. Hamlin, A. West, J. A. Kruse, D. A. Moser, T. W. Wilson (2022). Multivariate Patterns of Brain-Behavior Associations Across the Adult Lifespan. Aging. https://doi.org/10.18632/aging.203815
S. Bouhassoun, N. Poirel, N. Hamlin, G. E. Doucet (2022) The forest, the trees, and the leaves across adulthood: Age-related changes on a visual search task containing three-level hierarchical stimuli. Attention, Perception, & Psychophysics. https://doi.org/10.3758/s13414-021-02438-3
A. West, N. Hamlin, S. Frangou, T. W. Wilson, G. E. Doucet (2022) Person-based similarity index for cognition and its neural correlates in late adulthood: Implications for cognitive reserve. Cerebral Cortex. 32:397-407.
